Title Image

Black cumin oil, modes of action of thymoquinone against COVID-19, 2 new preclinical studies

Black cumin oil, modes of action of thymoquinone against COVID-19, 2 new preclinical studies

February 23, 2021 By Maria Hoch

In early February, two studies were published that explored the modes of action of thymoquinone against COVID-19.

Our member Manuela Alberth has pointed us to two exciting preclinical studies that were published in early February, thank you very much.

  1. The influence of thymoquinone on Covid 192.
  2. Thymoquinone: a TIe-breaker in SARS-CoV2 infected cancer patients.

 

 

Thymoquinone is a monoterpenoquinone found in black seed (Nigella sativa) essential oil, cold-pressed oil, and CO2 extract. Its excellent antioxidant and anti-inflammatory activity allows a number of possible cytoprotective applications. It also has interesting antitumor properties.

 

One of the new studies found that thymoquinone effectively binds to the ACE2 receptor expressed on the surface of many cells, preventing coronavirus from entering and infecting the cell. In addition, a previous study showed that thymoquinone could inhibit the viral protease enzyme, which could further enhance the antiviral effect.

 

The other study is a review article discussing the possible role of thymoquinone in cancer patients infected with coronavirus. It is argued that thymoquinone has a unique combination of antiviral and antitumor properties. At the same time, it can alleviate the systemic inflammation associated with both diseases as well as the toxicities associated with chemotherapy.

 

Computational and experimental studies show that thymoquinone blocks coronavirus entry in vitro

Here is the original link to the studies:

https://ijpha.wordpress.com/2021/02/12/the-impact-of-thymoquinone-on-covid-19/

No Comments

Post a Comment

Loading...